Eisa Mahyari

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Eisa Mahyari, Ph.D.

Contact

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CORE SKILLS

Management Statistics & Computer Science Biology & Medicine
- Project coordination - Machine Learning & AI - Single-cell & spatial OMICs
- Operational & cross-functional leadership - Fine-tuning of LLM on specialized domains - Translational research
- Multi-disciplinary collaboration - Software engineering - Reproduction & infertility
- Data-driven strategic planning & consultation - Statistical & mathematical modeling - Immunology, autoimmunity, & Gender-bias of immune function
- Budgeting & resource allocation - Biostatistics - Hormonal regulation of immune function
- Stakeholder communication - Cloud computing (Slurm, AWS, Google) - Infectious diseases HIV, MTb, Yellow Fever, Dengue, Zika, CMV, and SARS-CoV-2
- Grant writing - Translational & clinical trial data analytics - PBPK modeling & pharmacokinetics

Summary Statement

I am a computational biologist driven by applied machine learning and AI for translational biomedical research. I am an expert at statistical modeling and advanced data analysis. In medicine, I specialize in immunology, infectious diseases, and reproductive biology as a biologist. I enjoy leading diverse projects, coding, performing statistical analyses, and converting complex biological data into actionable insights alongside principal investigators and cross-disciplinary teams. I am most valued as an innovative and statistical thinker and methods, and my communication skills in collaborations with internal and external stakeholders.

As R. Assistant Professor at OHSU/ONPRC, I deploy computational pipelines, develop interactive data visualization platforms, secure and manage research funding through competitive grants, and lead the strategic development of AI/ML solutions for research. I also develop statistically based plans, projections, SOPs to manage internal and external functions.

My research in this role focuses on integrating high-dimensional multi-omics datasets, performing cross-species analysis, and employing statistical inference and computational omics to support clinical and preclinical initiatives. Furthermore, I actively consult across labs, providing technical training and mentorship to graduate students and guiding their research and career development.

My career has been defined by consistent advancement and a focus on statistics, machine learning, and advanced data analytics relevant to translational and clinical research. I have played a pivotal role in designing, implementing, and analyzing extensive research projects, combining wet lab and in silico methodologies to develop hypotheses and transform data into actionable outcomes. My work upholds rigorous quality control across various omics data types to ensure integrity and reproducibility. Through statistical consultations and analyses, I have contributed significantly to clinical study documentation, scientific publications, presentations, grants, and regulatory filings in academic and industry settings.

Currently, I am interested in leading and developing teams to create software, pipelines, and testing methodologies tailored for analyzing and translating complex biomedical data, supporting impactful translational research by integrating data types, and applying robust statistical methodologies and computational tools. With the advent of large language models (LLMs), such tasks and aims can be rapidly scaled; thus, my research includes fine-tuning, testing, and deploying specialized LLM for biomedical research.

Domains of Research Expertise & Interest

Technical skills

Professional Experience

2025 -

Computation Group Lead, Research Assistant Professor
Lab of Jacob D. Estes, Ph.D. - Vaccine & Gene Therapy Institute (VGTI), ONPRC-OHSU

2022 - 2024

Research Assistant Professor, Computational, OMICs, Translational Mammalian Reproduction
Lab of Donald F. Conrad, Ph.D. - Division of Genetics, ONPRC-OHSU

2018 - 2022

Computational Biologist, Molecular Immunopathology - Research Associate
Lab of Benjamin N. Bimber, Ph.D. - Primate Genetics, ONPRC-OHSU

2021 - 2022

Biostatistics & Computational Biology Consultant
Drug Development & Testing for Nonalcoholic Steatohepatitis (NASH) - CytoDyn, USA

2018 - 2022

Computational Biologist, Reproductive Biology - Research Associate
Lab of Donald F. Conrad, Ph.D. - Reproductive Genetics, ONPRC-OHSU

2016 - 2018 Doctoral Candidate, DMICE-BCB, OHSU. Developed novel machine learning framework for automated classification of rare cells in single-cell RNA-seq data. 2013 - 2016 Doctoral Student, DMICE-BCB, OHSU.

Research Involvement:

2008 - 2012 Sr. Research Associate, Louis Picker M.D., Vaccine & Gene Therapy Institute (VGTI), OHSU. Contribution: Performed experiments, analyzed flow cytometric data, performed statistical tests and developed reports and presentation materials.

2005 - 2007 Research Associate, Clinical Research Investigative Studies Program (CRISP) and Critical Care Academics Associates Program (CCAAP), OHSU. Contribution: Acquired clinical data from patient charts for ongoing studies and identified candidates for enrollment into qualifying research in the emergency department and the intensive care units.

Personal & Professional Attributes

Education

Software & Research Products

Awards and Honors

Accepted Abstracts, Poster, & Talks

Teaching & Mentorship Experience

Publications by year

Professional Affiliations

Attended Professional Conferences

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